User query
Users might select among the 118 C. elegans neuron types, visualize manually selected genes (one gene per line) or top 10 TFs (TFs ranking in the first 10 positions for the selected neuron type in any developmental stage). The expression cutoff allows to improve visualization. Update the plot is useful when the user does not notice input changes.
Expression heatmap
The expression heatmap will render the expression of queried genes, showing the manually input genes at the top and the top 10 TFs at the bottom. Top 10 TFs are TFs that ranked in the first 10 positions in any developmental stage.
WARNING: L4 expression values for dpy-20, cho-1, C30A5.16, eat-4, saeg-2, unc-47, unc-119, pha-1, F38B6.2, lin-15B, lin-15A, C30F8.3, gcy-35, unc-54, cex-1, rol-6, unc-53 are unreliable as they have been overexpressed to generate transgenic strains.
Protein expression
Protein expression with translational reporters for the selected post-mitotic neuronal type and its progenitor cell according to Ma et al., 2021
Ranking trajectory
Interactive plot showing the ranking of each TF from the selected input. Users can hover over points to know the exact ranking at each developmental stage. Individual TFs might be selected by double click on the gene name on the right. Broadly expressed TFs are not present